Product Description
Phospho-SMAD3(T179) Polyclonal Antibody | E-AB-68181 | Elabscience
Type: Phosphorylated antibody
Synonyms: HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3, SMAD3
Application: WB, IHC
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Stem Cells
Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic phosphorylated peptide around T179 of human SMAD3 (NP_005893.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 25 kDa/35 kDa/43 kDa/48 kDa
Molecular Weight(Observed): 48 kDa