Product Description
LRP5 Polyclonal Antibody | E-AB-12546 | Elabscience
Type: Polyclonal Antibody
Synonyms: BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Stem Cells
Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human LRP5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A