Product Description
ZAP70 Polyclonal Antibody | E-AB-53218 | Elabscience
Type: Polyclonal Antibody
Synonyms: 70 kDa zeta associated protein, 70 kDa zeta-associated protein, EC 2.7.10.2, FLJ17670, FLJ17679, Selective T cell defect, SRK, STD, Syk related tyrosine kinase, Syk-related tyrosine kinase, Truncated ZAP kinase, Tyrosine protein kinase ZAP70, Tyrosine-protein kinase ZAP-70, TZK, ZAP 70, ZAP70, ZAP70, Zeta chain associated protein kinase 70kD, Zeta chain associated protein kinase 70kDa, Zeta chain associated protein kinase 70kDa isoform 1, Zeta chain associated protein kinase 70kDa isoform 2, Zeta chain of T cell receptor associated protein kinase 70, Zeta chain TCR associated protein kinase 70kD, Zeta chain TCR associated protein kinase 70kDa
Application: WB, IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Immunology, Signal Transduction, Tags and Cell Markers
Background: Zeta-associated protein (ZAP)-70, a member of the Syk family of tyrosine kinases, plays an important role in T-cell receptor signaling, natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human ZAP70
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 70 kDa
Molecular Weight(Observed): Refer to figures