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Product Description
Phospho-NFKBIA(S32) Polyclonal Antibody | E-AB-68197 | Elabscience
Type: Phosphorylated antibody
Synonyms: IKBA, MAD-3, NFKBI, IKB alpha, NFKBIA, EDAID2
Application: WB
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signaling transduction
Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic phosphorylated peptide around S32 of human NFKBIA (NP_065390.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 35 kDa
Molecular Weight(Observed): 39 kDa/41 kDa
