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Product Description
TBX21 Polyclonal Antibody | E-AB-67622 | Elabscience
Type: Polyclonal Antibody
Synonyms: TBX21, T-PET, T-bet, TBET, TBLYM, T-box 21
Application: WB
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: N/A
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human TBX21 (NP_037483.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 58 kDa
Molecular Weight(Observed): 58 kDa
