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Product Description
Anti- APEX1 Antibody | FNab00479 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Immunogen: APEX nuclease (multifunctional DNA repair enzyme) 1
synonyms: APE, APE1, APEX, APX, HAP1, REF1
Molecular weight (observed) : 39 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200
Research Area: Cardiovascular, Metabolism
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