Product Description
Anti- DNMT3L Antibody | FNab02486 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Immunogen: DNA (cytosine-5-) -methyltransferase 3-like
synonyms: N/A
Molecular weight (observed) : 44kd and 70kd
Reactivity Species: Human
Tested Application: ELISA, WB, IP
Recomended Dillution : WB: 1:500-1:2000
Research Area: Epigenetics, Metabolism, Developmental biology