Product Description
Anti- NCOA3 Antibody | FNab05589 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs) . Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
Immunogen: nuclear receptor coactivator 3
synonyms: AIB1, BHLHE42, RAC3, TRAM1
Molecular weight (observed) : 160kd
Reactivity Species: Human
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Metabolism