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Product Description
Anti- MNAT1 Antibody | FNab05252 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Immunogen: menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
synonyms: CAP35, MAT1, RNF66
Molecular weight (observed) : 36 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Research Area: Cell Division and Proliferation, Metabolism
