Product Description
Anti- PFTK1 Antibody | FNab06344 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: PFTK1 is a Cdc2-related protein kinase, also named as PFTAIRE1, CDK14 and belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It acts as a cyclin-dependent kinases that regulates cell cycle progression and cell proliferation. The PFTK1 protein shows high homology with mouse Pftaire1, a Cdc2-related protein expressed primarily in the postnatal and adult nervous system (PMID:9202329) . The protein contains 2 predicted nuclear localization signals that the N-terminal nuclear localization signals do not play a role in vivo (PMID:11313143) . It has 3 isoforms produced by alternative splicing. This antibody is specific to PFTK1.
Immunogen: PFTAIRE protein kinase 1
synonyms: CDK14, hPFTAIRE1, KIAA0834, PFTAIRE protein kinase 1, PFTAIRE1, PFTK1
Molecular weight (observed) : 48-53 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:500
Research Area: Cell Division and Proliferation, Metabolism