Euro
USD
British Pound
NULL
Product Description
Anti- TSG101 Antibody | FNab09040 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Immunogen: tumor susceptibility gene 101
synonyms: ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23
Molecular weight (observed) : 44 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Research Area: Cell Division and Proliferation, Cardiovascular, Metabolism, Developmental biology
