Product Description
Anti- WDR24 Antibody | FNab09488 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238, PubMed:27166823) . Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway (PubMed:23723238) . Functions downstream of and is regulated by amino acid sensors like SESN2 (PubMed:26449471, PubMed:26586190) . In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823) .
Immunogen: WD repeat domain 24
synonyms: C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24
Molecular weight (observed) : 102 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200
Research Area: Cell Division and Proliferation