Product Description
Anti- HARS2 Antibody | FNab03759 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
Immunogen: histidyl-tRNA synthetase 2, mitochondrial (putative)
synonyms: HARSL, HARSR, HO3
Molecular weight (observed) : 50 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Research Area: Metabolism