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Product Description
Anti- AHR Antibody | FNab00231 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene) . Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Immunogen: aryl hydrocarbon receptor
synonyms: Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76
Molecular weight (observed) : 105 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, IF
Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Research Area: Epigenetics, Signal Transduction, Metabolism
