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Product Description
Anti- HDAC3 Antibody | FNab10321 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Immunogen: histone deacetylase 3
synonyms: HD3, RPD3, RPD3-2, HDAC3
Molecular weight (observed) : 49 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC, WB
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Research Area: Epigenetics, Cardiovascular, Metabolism
