Product Description
Anti- SMARCA4 Antibody | FNab08004 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
synonyms: BAF190A, BRG1, SNF2B, SNF2L4
Molecular weight (observed) : 180 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC, IF, WB
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:50
Research Area: Epigenetics, Stem Cells, Metabolism