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Product Description
Anti- UBR2 Antibody | FNab09209 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Immunogen: ubiquitin protein ligase E3 component n-recognin 2
synonyms: BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2
Molecular weight (observed) : 66 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:200-1:2000; IF：1：10-1:100; IHC: 1:20-1:200
Research Area: Epigenetics, Metabolism, Developmental biology
