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Product Description
Anti- USP21 Antibody | FNab09318 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity) . Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates (PubMed:10799498) . Deubiquitinates BAZ2A/TIP5 leading to its stabilization (PubMed:26100909) .
Immunogen: ubiquitin specific peptidase 21
synonyms: Deubiquitinating enzyme 21, Ubiquitin thiolesterase 21, USP16, USP21, USP23
Molecular weight (observed) : 63 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC, IP
Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200
Research Area: Epigenetics, Metabolism
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