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Product Description
Anti- BAX Antibody | FNab00811 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 5F4
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Immunogen: BCL2-associated X protein
synonyms: BCL2L4
Molecular weight (observed) : 21 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP, FC
Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Research Area: Neuroscience, Cancer, Developmental biology
