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Product Description
Anti- Cytokeratin 18 Antibody | FNab02206 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 6E3
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
Immunogen: keratin 18
synonyms: CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18
Molecular weight (observed) : 48 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IHC, IP
Recomended Dillution : WB: 1:5000-1:30000; IHC: 1:500-1:1000; IF: 1:100-1:300
Research Area: Cancer, Immunology, Cardiovascular
