Product Description
Anti- EGFR Antibody | FNab10146 | FineTest
Form: liquid
Purification: protein A+G purified
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 2C9
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Immunogen: epidermal growth factor receptor
synonyms: EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1
Molecular weight (observed) : 140-160 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:2000 - 1:10000; IHC: 1:100 - 1:1000
Research Area: Signal Transduction, Immunology, Cancer