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Product Description
Anti- Prealbumin/transthyretin Antibody | FNab06761 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 8E4
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis) . Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR), hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1) . In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)
Immunogen: transthyretin
synonyms: ATTR, HsT2651, PALB, Prealbumin, TBPA, transthyretin, TTR
Molecular weight (observed) : 16kd
Reactivity Species: Human
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200
Research Area: Cancer, Immunology, Signal Transduction
