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Product Description
Anti- Cytochrome c Antibody | FNab098271 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 3G4
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Immunogen: Cytochrome c
synonyms: CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4
Molecular weight (observed) : 12 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:5000-1:30000; IHC: 1:100-1:1000
Research Area: Cardiovascular, Metabolism
