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Product Description
Anti- KCNN4 Antibody | FNab04499 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 8A11
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990) . Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614) .
Immunogen: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
synonyms: IK1, IKCA1, KCA4, SK4
Molecular weight (observed) : 48 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500 - 1:2000
Research Area: Neuroscience, Developmental biology
