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Product Description
Anti- p38 MAPK Antibody | FNab06077 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 6D2
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: MAPK14 (mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T (H) 17 differentiation and inflammation (PMID:22231518) . It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell (PMID:21198398) . This protein has 4 isoforms produced by alternative splicing.
Immunogen: mitogen-activated protein kinase 14
synonyms: CSAID binding protein, CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, Mxi2, p38, p38ALPHA, PRKM14, PRKM15, RK, SAPK2A
Molecular weight (observed) : 38 kDa
Reactivity Species: Human, Pig
Tested Application: ELISA, WB, IF, IHC
Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:100-1:400
Research Area: Immunology, Cardiovascular, Metabolism, Signal Transduction
