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Product Description
Anti- PDCD4 Antibody | FNab06240 | FineTest
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 3B7
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .
Immunogen: programmed cell death 4 (neoplastic transformation inhibitor)
synonyms: H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a
Molecular weight (observed) : 56 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC, FC, IP
Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:20-1:200
Research Area: Metabolism
