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Product Description
Anti- BACE1 Antibody | FNab00781 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Immunogen: beta-site APP-cleaving enzyme 1
synonyms: BACE, KIAA1149
Molecular weight (observed) : 70-75 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IHC
Recomended Dillution : WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:100-1:400
Research Area: Neuroscience, Metabolism
