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Product Description
Anti- HTRA2 Antibody | FNab04070 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Immunogen: HtrA serine peptidase 2
synonyms: HtrA serine peptidase 2, HTRA2, OMI, PARK13, PRSS25, Serine protease 25, Serine proteinase OMI
Molecular weight (observed) : 36 kDa
Reactivity Species: Human, Mouse, Rat, Monkey
Tested Application: ELISA, WB, IF, IP, IHC
Recomended Dillution : WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Research Area: Neuroscience, Signal Transduction, Metabolism, Developmental biology
