Product Description
Anti- SCNN1A Antibody | FNab07648 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. It has been reported that full-length SCNN1A protein can be cleaved into 65-and 30-kDa fragments.
Immunogen: sodium channel, nonvoltage-gated 1 alpha
synonyms: Alpha ENaC, Alpha NaCH, ENaCa, ENaCalpha, FLJ21883, SCNEA, SCNN1, SCNN1A
Molecular weight (observed) : 65kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Research Area: Neuroscience