Euro
USD
British Pound
NULL
Product Description
Anti- VMAT2 Antibody | FNab09418 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: VMAT2 is a vesicular monoamine transporter that is responsible for the uptake and storage of monoamines (dopaine, norepinephrine, epinephrine, histamine and serotonin) in neurons, endocrine cells, and tumors deriving from these cells. Histamine-producing endocrine tumors (gastric carcinoids) expressed VMAT2 almost exclusively, thus VMAT2 is useful in classification of neuroendocrine tumors. Reduced expression of VMAT2 has often been observed in Parkinson’s diseased (PD) brain, and detection of VMAT2 can be used to reflect the dopamine neuron loss and predict the disease process. VMAT2 migrated as a major band of 65-75 kDa and a minor band of 55-60 kDa, representing the glycosylated form and native form.
Immunogen: solute carrier family 18 (vesicular monoamine), member 2
synonyms: Monoamine transporter, SLC18A2, SVAT, SVMT, VAT2, Vesicular amine transporter 2, VMAT2
Molecular weight (observed) : 56 kDa, 66 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IHC, IP
Recomended Dillution : WB: 1:200-1:2000
Research Area: Neuroscience
