Product Description
Anti- PKMYT1 Antibody | FNab06497 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Immunogen: protein kinase, membrane associated tyrosine/threonine 1
synonyms: MYT1
Molecular weight (observed) : 55 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, IF, WB, FC, IP
Recomended Dillution : WB: 1:500-1:2000
Research Area: Metabolism