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Product Description
Anti- ZBTB38 Antibody | FNab09593 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3') . Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner (PubMed:16354688) . Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359) . Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity) .
Immunogen: zinc finger and BTB domain containing 38
synonyms: ZBTB38, FLJ31131, FLJ35036, CIBZ, FLJ22332
Molecular weight (observed) : 134 kDa
Reactivity Species: Human
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200
Research Area: Metabolism
