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Product Description
Anti- ZFYVE19 Antibody | FNab09629 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Immunogen: zinc finger, FYVE domain containing 19
synonyms: FLJ14840, MPFYVE, ZFYVE19
Molecular weight (observed) : 52 kDa
Reactivity Species: Human
Tested Application: ELISA, WB, IP, IHC
Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:20-1:200
Research Area: Metabolism
