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Product Description
Anti- PAG1 Antibody | FNab06112 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Immunogen: phosphoprotein associated with glycosphingolipid microdomains 1
synonyms: CBP, PAG
Molecular weight (observed) : 50-60 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC, IP
Recomended Dillution : WB: 1:500-1:2000
Research Area: Immunology, Signal Transduction
