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Product Description
Anti- Renin receptor, ATP6AP2 Antibody | FNab07241 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: ATP6AP2, also named as ATP6IP2, CAPER, ELDF10, N14F, ATP6M8-9, Renin receptor and prorenin receptor, is believed to potentiate the renin–angiotensin system (RAS), conferring to prorenin, a likely pathological role at tissue level. The PRR has been identified in the microvascular endothelial cells of the retina, in which it seems to be involved in pathological neovascularization processes. The present study demonstrates for the first time that the PRR is expressed in human ATP6AP2 and suggests a molecular mechanism by which hypertension may exacerbate the pathology of dry AMD.
Immunogen: ATPase, H+ transporting, lysosomal accessory protein 2
synonyms: APT6M8 9, ATP6AP2, ATP6IP2, ATP6M8 9, CAPER, ELDF10, HT028, M8 9, MRXE, MSTP009, N14F, PRR, PSEC0072, Renin receptor, RENIN RECEPTOR, ATP6AP2, Renin/prorenin receptor, V ATPase M8.9 subunit, XMRE
Molecular weight (observed) : 47kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IHC
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200
Research Area: Signal Transduction, Metabolism
