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Product Description
Anti- SPHK1 Antibody | FNab08173 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: sphingosine kinase 1
synonyms: SPHK, SPK
Molecular weight (observed) : 55 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Research Area: Cardiovascular, Signal Transduction
