Product Description
Anti- TLR3 Antibody | FNab08726 | FineTest
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Immunogen: toll-like receptor 3
synonyms: N/A
Molecular weight (observed) : N/A
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : IHC: 1:20-1:200
Research Area: Immunology, Signal Transduction, Developmental biology