Product Description
TWEAK protein | 30R-AT062 | Fitzgerald
Activity Code: ACTIVE
Product Type: Proteins
Product Subtype: Recombinant Proteins
Research Area: Cancer
Short Description: Purified recombinant Human TWEAK protein
Immunogen: N/A
Host: N/A
Specificity: N/A
Cross Reactivity: N/A
Isotype: N/A
IClone: N/A
Species: Human
Residues: Region of TWEAK protein corresponding to amino acids MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH.
Tag/conjugate: N/A
Protein Type: Recombinant
Expression System: E.coli
Grade & Purity: > 98% pure
Methode of Purification: N/A
Source: N/A
Concentration: N/A
Form & Buffer: Lyophilized from 10mM Na3PO4, pH 7.5 with 100mM L-Arginine. Reconstitute in 10mM Na3PO4, pH 7.5 to a concentration of 1.0 mg/ml.
Storage: Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Shipping Information: *Blue Ice*
Applications: User optimized
Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of IL-8 production by Human PBMC is less than 10 ng/ml. Assay #2: TWEAK weakly induces the death of HT29 cells when cultured in the presence of IFN-gamma. The ED50 for this effect is between 30-45 ng/ml.
Usage Recommendations: N/A
Assay Information: N/A