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Product Description
Recombinant Mouse CSF-1R Protein (C-His Tag) | PM0068M1 | Leading Biology
Short Description: Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS) . It is a receptor for a cytokine called colony stimulating factor 1. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSF1R through a process of oligomerization and trans-phosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
Product Type: Cytokine
Form: lyophilized
Purity: Greater than 95% by SDS-PAGE
Storage: -70°C
Buffer: 0.2 μm filtered PBS, pH7.4
