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![Phospho-PBK (Y74) Antibody [APR32057G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/872302/1164369/logo__92149.1659788186__49588.1659868416.png?c=2 "Phospho-PBK (Y74) Antibody [APR32057G]"){kind=logo}
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Product Description
Phospho-PBK (Y74) Antibody [APR32057G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This PBK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y74 of human PBK.
Cellular Localisation: N/A
Molecular Weight: 36085
Clone: Polyclonal
Gene Name: PBK
Gene ID: 55872
Function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage.
Summary: Tissue Location: Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: DB
Dilution: DB--1:500
Synonyms: Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinase, PBK, TOPK
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