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![HIST1H1B Antibody (N-term) [APR32141G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/872386/1164453/logo__92149.1659788186__31898.1659868636.png?c=2 "HIST1H1B Antibody (N-term) [APR32141G]"){kind=logo}
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Product Description
HIST1H1B Antibody (N-term) [APR32141G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This HIST1H1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-60 amino acids from the N-terminal region of human HIST1H1B.
Cellular Localisation: Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin
Molecular Weight: 22580
Clone: Polyclonal
Gene Name: H1-5 (HGNC:4719)
Gene ID: 3009
Function: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) .
Summary: Tissue Location: Ubiquitous. Expressed in the majority of the cell lines tested and in testis.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: FC, WB
Dilution: WB--1:1000 FC--1:10~50
Synonyms: Histone H15, Histone H1a, Histone H1b, Histone H1s-3, HIST1H1B, H1F5
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