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Product Description
CREB3L4 Antibody (M01) [AMM22162G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H, Rat
Specificity: This CREB3L4 antibody is generated from mice immunized with a recombinant between 1-300 amino acids from the region of human CREB3L4.
Cellular Localisation: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single- pass type II membrane protein. Note=May also be located in Golgi apparatus
Molecular Weight: 43432
Clone: Monoclonal
Gene Name: CREB3L4
Gene ID: 148327
Function: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity) .
Summary: Tissue Location: According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines Expressed in prostatic luminal epithelial cells (at protein level) Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia) . According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, AIbZIP, Attaching to CRE-like 1, ATCE1, Cyclic AMP-responsive element-binding protein 4, CREB-4, cAMP-responsive element-binding protein 4, Transcript induced in spermiogenesis protein 40, Tisp40, hJAL, Processed cyclic AMP-responsive element-binding protein 3-like protein 4, CREB3L4, AIBZIP, CREB4, JAL
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