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Product Description
FOLR2 Antibody [AMM22266G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This FOLR2 antibody is generated from a mouse immunized with a recombiant protein from human FOLR2.
Cellular Localisation: Cell membrane; Lipid-anchor, GPI-anchor. Secreted
Molecular Weight: 29280
Clone: Monoclonal
Gene Name: FOLR2
Gene ID: 2350
Function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Summary: Tissue Location: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000-1:2000
Synonyms: Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
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