Euro
USD
British Pound
NULL
![MME Antibody (Center) [AMM22233G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/870594/1162661/logo__92149.1659788186__00064.1659866723.png?c=2 "MME Antibody (Center) [AMM22233G]"){kind=logo}
![MME Antibody (Center) [AMM22233G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/870594/1162661/logo__92149.1659788186__00064.1659866723.png?c=2 "MME Antibody (Center) [AMM22233G]"){kind=logo}
Product Description
MME Antibody (Center) [AMM22233G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.
Cellular Localisation: Cell membrane; Single-pass type II membrane protein
Molecular Weight: 85514
Clone: Monoclonal
Gene Name: MME
Gene ID: 4311
Function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535) . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991) . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675) . Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP (1- 32) ) (PubMed:2531377, PubMed:2972276, PubMed:16254193) . Displays UV- inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, FC, IHC-P-Leica
Dilution: IHC-P-Leica--1:1000 FC--1:25 IHC--1:1000 WB--1:4000
Synonyms: Neprilysin, 3.4.24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
![MME Antibody (Center) [AMM22233G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/870594/1162661/logo__92149.1659788186__00064.1659866723.png?c=2 "MME Antibody (Center) [AMM22233G]"){kind=logo}
![MME Antibody (Center) [APR05889G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/868054/1160121/logo__92149.1659788186__54523.1659864215.png?c=2 "MME Antibody (Center) [APR05889G]"){kind=logo}
![MME Antibody (Center) [APR04666G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/869373/1161440/logo__92149.1659788186__92012.1659865585.png?c=2 "MME Antibody (Center) [APR04666G]"){kind=logo}
![MME Antibody (Center) [APR04681G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/869432/1161499/logo__92149.1659788186__71515.1659865632.png?c=2 "MME Antibody (Center) [APR04681G]"){kind=logo}
![MME Antibody (Center) [APR04662G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/869374/1161441/logo__92149.1659788186__76205.1659865586.png?c=2 "MME Antibody (Center) [APR04662G]"){kind=logo}
![MME Antibody (Center) [APR03424G]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/863816/1155883/logo__92149.1659788186__79181.1659859914.png?c=2 "MME Antibody (Center) [APR03424G]"){kind=logo}