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Product Description
Nephrin Antibody [AMM22111G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This Nephrin antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1088-1117 amino acids from human Nephrin.
Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm between podocyte foot processes. Also associated with podocyte apical plasma membrane.
Molecular Weight: 134742
Clone: Monoclonal
Gene Name: NPHS1
Gene ID: 4868
Function: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity) .
Summary: Tissue Location: Specifically expressed in podocytes of kidney glomeruli
Form: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IF
Dilution: N/A
Synonyms: Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
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