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Product Description
PHB Antibody [APR09107G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H, M, Rat
Specificity: This antibody is generated from a mice immunized with a recombinant protein between 1-205 amino acids from human.
Cellular Localisation: Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane
Molecular Weight: 29804
Clone: Monoclonal
Gene Name: PHB (HGNC:8912)
Gene ID: 5245
Function: Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:28017329, PubMed:31522117) . Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner (By similarity) . Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity) .
Summary: Tissue Location: Widely expressed in different tissues.
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB, IHC-P
Dilution: IHC-P--1:100~500 WB--1:1000
Synonyms: Prohibitin, PHB
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