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Product Description
THEM2 Antibody [AMM08196G] | Leading Biology
Product Category: Monoclonal Antibodies
Host: Mouse
Species Reactivity: H
Specificity: This THEM2 monoclonal antibody is generated from mouse immunized with THEM2 recombinant protein.
Cellular Localisation: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9CQR4}. Mitochondrion {ECO:0000250|UniProtKB:Q9CQR4}. Nucleus {ECO:0000250|UniProtKB:Q9CQR4} Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9CQR4} Note=During interphase, found both in the nucleus and in the cytoplasm At mitosis, localizes to the spindle. Colocalizes with tubulin {ECO:0000250|UniProtKB:Q9CQR4}
Molecular Weight: 14960
Clone: Monoclonal
Gene Name: ACOT13 (HGNC:20999)
Gene ID: 55856
Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545) . Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (By similarity) (PubMed:16934754, PubMed:19170545) . Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3, 4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity) (PubMed:16934754, PubMed:19170545) . May play a role in controlling adaptive thermogenesis (By similarity) .
Summary: N/A
Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Acyl-coenzyme A thioesterase 13, Acyl-CoA thioesterase 13, 312-, Thioesterase superfamily member 2, Acyl-coenzyme A thioesterase 13, N-terminally processed, ACOT13, THEM2
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