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Product Description
NKAP Antibody (C-term) [APR30945G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.
Cellular Localisation: Nucleus.
Molecular Weight: 47138
Clone: Polyclonal
Gene Name: NKAP
Gene ID: 79576
Function: Acts as a transcriptional repressor (PubMed:14550261, PubMed:19409814, PubMed:31587868) . Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development (PubMed:19409814) . Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch- regulated SKP2 promoter.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: NF-kappa-B-activating protein, NKAP
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