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Product Description
PSMB3 Antibody (Center) [ApR04876G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This PSMB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-185 amino acids from the Central region of human PSMB3.
Cellular Localisation: Cytoplasm. Nucleus
Molecular Weight: 22949
Clone: Polyclonal
Gene Name: PSMB3
Gene ID: 5691
Function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Proteasome subunit beta type-3, Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain, PSMB3
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