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Product Description
RFX2 Antibody (C-term) [APR31023G] | Leading Biology
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This RFX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human RFX2.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:B2GV50, ECO:0000255|PROSITE-ProRule:PRU00858}. Cytoplasm {ECO:0000250|UniProtKB:B2GV50}. Note=Mainly expressed in the nucleus and at lower level in cytoplasm. {ECO:0000250|UniProtKB:B2GV50}
Molecular Weight: 79987
Clone: Polyclonal
Gene Name: RFX2
Gene ID: 5990
Function: Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity) . Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC (0-3N) RGYAAC-3' present on promoters (PubMed:10330134) . Probably activates transcription of the testis-specific histone gene H1-6 (By similarity) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: DNA-binding protein RFX2, Regulatory factor X 2, RFX2
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